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Item number: Cay18383-1

NVP-BEP800 is an inhibitor of heat shock protein 90 (Hsp90, IC50 = 58 nM for recombinant human Hsp90beta). It is selective for Hsp90 over the chaperones GRP94 and TRAP1 (IC50s = 4.1 and 5.5 µM, respectively). NVP-BEP800 inhibits the growth of BT474, SK-BR-3, MCF-7, MDA-MB-157, MDA-MB-231, MDA-MB-468, and BT-20...

Keywords:	2-amino-4-[2,4-dichloro-5-[2-(1-pyrrolidinyl)ethoxy]phenyl]-N-ethyl-thieno[2,3-d]pyrimidine-6-carboxamide
Application:	Hsp90 beta inhibitor
CAS	847559-80-2
MW:	480.4 D

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