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Itraconazole
Item number: Cay13288-25
Itraconazole is an antifungal agent and inhibitor of hedgehog signaling (IC50 = 800 nM). It binds to 14-alpha sterol demethylase/CYP51 isoform B (AF51B, Kd = 31 nM for A. fumigatus enzyme expressed in E. coli) and inhibits ergosterol biosynthesis in C. neoformans (IC50 = 6 nM after a 16-hour incubation). It inhibits...
| Keywords: | 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl... |
| Application: | Hedgehog signaling antagonist |
| CAS | 84625-61-6 |
| MW: | 705.6 D |
From 40.00€
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Itraconazole
Item number: LKT-I7870.1
Triazole, 14-alpha demethylase inhibitor, Smo modulator.
| Keywords: | Oriconazole, Itrizole, Sporanox, Triasporin, 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-... |
| Application: | Antifungal agent |
| CAS | 84625-61-6 |
| MW: | 705,63 D |
From 109.00€
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