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delta-secretase inhibitor 11
delta-secretase inhibitor 11

Item number: TGM-T9713-100mg

Description: delta-secretase inhibitor 11 is an inhibitor of delta-secretase and can be used as a lead compound for translational development of AD treatment. Target: Caspase, Beta Amyloid. Smiles: Nc1ccc(N2CCOCC2)c2nonc12. References: Ju Wang, et al. Pharmacological inhibition of asparaginyl endopeptidase by...
Application: delta-secretase (legumain, asparaginyl endopeptidase, AEP) inhibitor
CAS 842964-18-5
MW: 220.23 D
From 31.00€ *
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delta-Secretase Inhibitor 11
delta-Secretase Inhibitor 11

Item number: Cay38524-10

delta-Secretase inhibitor 11 is an inhibitor of delta-secretase (IC50 = 0.7 µM), also known as asparagine endopeptidase (AEP) and legumain. It is selective for delta-secretase over cathepsin S, cathepsin L, caspase-3, and caspase-8 (IC50s = >200, >200, 31.86, and 86.71 µM, respectively). delta-Secretase inhibitor 11...
Keywords: 7-(4-morpholinyl)-2,1,3-benzoxadiazol-4-amine
Application: Legumain (LGMN)/asparaginyl endopeptidase inhibitor
CAS 842964-18-5
MW: 220.2 D
From 78.00€ *
Review