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Item number: TGM-T84541-10mg

Description: Vinclozolin M2, an active metabolite of vinclozolin, is generated through successive esterase activity and decarboxylation in C. elegans, as well as decarboxylation in human liver microsomes. It functions as an antagonist to the mineralocorticoid (IC50= 1,400 nM) and androgen receptors (IC50= 0.17 nM),...

Keywords:	M2
Application:	Dicarboximide fungicide, rat androgen receptor antagonist
CAS	83792-61-4
MW:	260.1 D

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Vinclozolin M2

Item number: Cay10007452-5

Vinclozolin M2 is an active metabolite of vinclozolin (Cay-23939). It is formed from vinclozolin by successive esterase activity and decarboxylation of vinclozolin in C. elegans and by decarboxylation in human liver microsomes. Vinclozolin M2 is an antagonist of the mineralocorticoid receptor (IC50 = 1,400 nM) and...

Keywords:	M2, N-(3,5-dichlorophenyl)-2-hydroxy-2-methyl-3-butenamide
Application:	Dicarboximide fungicide, rat androgen receptor antagonist
CAS	83792-61-4
MW:	260.1 D

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