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Item number: Cay16761-1

AS-1842856 is a potent inhibitor of forkhead box class O transcription factor 1 (FoxO1, IC50 = 33 nM in HepG2 cells). Inhibition of FoxO1-mediated transactivation with AS-1842856 leads to a dose-dependent decrease in expression of glucose-6 phosphatase (G6Pase) and phosphoenolpyruvate carboxykinase (PEPCK) mRNA and...

Keywords:	FOXO1 Inhibitor, 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Application:	Foxo1 Inhibitor
CAS	836620-48-5
MW:	347.4 D

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