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Item number: Cay31523-10

GLX-351322 is an inhibitor of NADPH oxidase 4 (NOX4, IC50 = 5 µM). It is selective for NOX4 over NOX2 (IC50 = 40 µM). GLX-351322 (10 µM) reduces glucose-induced production of reactive oxygen species (ROS) and cytotoxicity in isolated human pancreatic islets. It decreases blood glucose levels in an intravenous...

Keywords:	2-[[2-[4-(2-furanylcarbonyl)-1-piperazinyl]acetyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid, ethyl ester
Application:	NOX4 inhibitor
CAS	835598-94-2
MW:	431.5 D

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