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CID-16020046

Item number: Cay15247-1

CID-16020046 is a GPR55 inverse agonist that antagonizes GPR55 constitutive activity with an IC50 value of 15 µM. It inhibits GPR55-mediated ERK1/2 phosphorylation, LPI-induced Ca2+ signaling (IC50 = 0.21 µM in HEK-GPR55 cells), and GPR55-mediated transcription factor activation. It does not affect ERK1/2...

Keywords:	4-[4,6-dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-benzoic acid
Application:	GPR55 inverse agonist
CAS	834903-43-4
MW:	425.4 D

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