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Item number: TGM-T10979-100mg

Description: DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 µM, demonstrating at least 100-fold higher affinity over TREK1/TRAAK channels. Target: Potassium Channel, Chloride channel. Smiles:...

CAS	82749-70-0
MW:	427.36 D

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DCPIB

Item number: Cay34064-5

DCPIB is an inhibitor of volume-regulated anion channels (VRAC). It inhibits the swelling-induced chloride current (ICl,swell) in bovine pulmonary artery endothelial cells (IC50 = 4.1 µM). DCPIB inhibits the VRAC subunit leucine-rich containing 8A (LRRC8A, IC50 = 20.9 µM) and inhibits sphingosine-1-phosphate-induced...

Keywords:	4-[(2-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]-butanoic acid
Application:	VRAC inhibitor
CAS	82749-70-0
MW:	427.4 D

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