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FEN1-IN-1
Item number: TGM-T15274-10mg
Description: FEN1-IN-1 (LNT-1) is an inhibitor of flap endonuclease 1 (FEN1). FEN1-IN-1 binds to the active site of FEN1. It partly achieves inhibition by the co-ordination of Mg2+ ions. Target: Others. Smiles: On1c(=O)n(CC2COc3ccccc3O2)c2ccsc2c1=O. References: Ward TA, et al. Small molecule inhibitors uncover...
| Keywords: | LNT-1 |
| Application: | FEN1 inhibitor |
| CAS | 824983-91-7 |
| MW: | 332.33 D |
From 31.00€
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LNT 1
Item number: Cay35803-1
LNT 1 is an inhibitor of flap endonuclease 1 (FEN1, IC50 = 0.011 µM). It is selective for FEN1 over xeroderma pigmentosum G (IC50 = 0.292 µM). LNT 1 (3 and 6 µM) enhances methyl methanesulfonate-induced DNA damage and cell death in T24 bladder cancer cells.Formal Name:...
| Keywords: | 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-3-hydroxy-thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione |
| Application: | FEN1 inhibitor |
| CAS | 824983-91-7 |
| MW: | 332.3 D |
From 90.00€
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