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FMK
Item number: TGM-TQ0310-100mg
Description: FMK is an irreversible inhibitor of RSK2 kinase. Target: S6 Kinase. Smiles: Cc1ccc(cc1)-c1c(C(=O)CF)n(CCCO)c2ncnc(N)c12. References: Cuello F, et al. Evidence for direct regulation of myocardial Na+/H+ exchanger isoform 1 phosphorylation and activity by 90-kDa ribosomal S6 kinase (RSK): effects of the...
| Application: | RSK2 inhibitor |
| CAS | 821794-92-7 |
| MW: | 342.37 D |
From 67.00€
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FMK
Item number: Cay9000887-5
FMK is an inhibitor of p90 ribosomal S6 kinase 3alpha (RSK2, IC50 = 15 nM). It inhibits the C-terminal domain (CTD) kinase activity of RSK2 and inhibits EGF-induced phosphorylation of RSK2 Ser386 in serum-starved COS-7 cells (EC50 = ~200 nM). FMK (6 µM) reduces invasion, but not proliferation, of M4e, 212LN, and 37B...
| Keywords: | Fluoromethyl Ketone, Fluoromethyl Ketone-MEA, FMK-MEA,... |
| Application: | RSK2 inhibitor |
| CAS | 821794-92-7 |
| MW: | 342.4 D |
From 61.00€
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