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Item number: Cay15294-10

Roxadustat is an analog of 2-OG that has been developed as an inhibitor of HIF-PHs. While little has been published regarding the actions of this compound, similar HIF-PH inhibitors suppress HIF degradation and in this way induce erythropoietin expression, promoting erythropoiesis or preventing anemia in vivo.Formal...

Keywords:	ASP1517, Roxadustat, N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-glycine
Application:	Presumed HIF-PH inhibitor
CAS	808118-40-3
MW:	352.4 D

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Roxadustat

Item number: TGM-T2515-10mg

Description: Roxadustat (FG-4592) is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), with potential anti-anemic activity. Target: HIF/HIF Prolyl-Hydroxylase, HIF, Ferroptosis. Smiles: Cc1nc(C(=O)NCC(O)=O)c(O)c2ccc(Oc3ccccc3)cc12. References: 1. Seeley, TW, et al. U.S. Pat....

Keywords:	ASP1517, FG-4592
CAS	808118-40-3
MW:	352.34 D

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