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AA-861
AA-861

Item number: Cay13263-1

AA-861 is an inhibitor of 5-lipoxygenase (5-LO, IC50 = 0.8 µM). It is greater than 100-fold selective for 5-LO over 12-LO and cyclooxygenase (COX). AA-861 inhibits the production of 5-HETE and leukotriene B4 (LTB4, Cay-20110, Cay-10007240) induced by A23187 (Cay-22030) with IC50 values of 0.03 and 0.08 µM,...
Keywords: A-61589, Docebenone, 2-(12-hydroxy-5,10-dodecadiyn-1-yl)-3,5,6-trimethyl-2,5-cyclohexadiene-1,4-dione
Application: 5-LO inhibitor
CAS 80809-81-0
MW: 326.4 D
From 247.00€ *
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Docebenone
Docebenone

Item number: TGM-T15155-100mg

Description: Docebenone is a selective and orally active inhibitor of 5-LO. Target: Others. Smiles: C(CCCC#CCCCC#CCO)C1=C(C)C(=O)C(C)=C(C)C1=O. References: Nam YH, et al. Leukotriene B(4) receptors BLT1 and BLT2 are involved in interleukin-8 production in human neutrophils induced by Trichomonas vaginalis-derived...
Keywords: AA 861
Application: Targets arachidonate 5-lipoxygenase [EC:1.13.11.34] (ALOX5)
CAS 80809-81-0
MW: 326.43 D
From 368.00€ *
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