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AZD 1981
Item number: Cay20763-5
AZD 1981 is a DP2/CRTH2 receptor antagonist (IC50 = 3.98 nM). It is selective for DP2 over a panel of receptors, ion channels, transporters, and enzymes, including DP1, COX-1, and COX-2, at 10 µM. AZD 1981 (3-100 nM) inhibits increases in the expression of CD11b, a cell adhesion molecule, induced by...
| Keywords: | 4-(acetylamino)-3-[(4-chlorophenyl)thio]-2-methyl-1H-indole-1-acetic acid |
| Application: | PGD2 receptor antagonist |
| CAS | 802904-66-1 |
| MW: | 388.9 D |
From 72.00€
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AZD1981
Item number: TGM-T6399-100mg
Description: AZD1981 is an effective and specific CRTh2 (DP2) receptor antagonist (IC50: 4 nM), showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1. AZD1981 has been used in trials studying the treatment and basic science of Asthma, Postmenopausal, Pharmakokinetic, Asthma...
| Application: | PGD2 receptor antagonist |
| CAS | 802904-66-1 |
| MW: | 388.87 D |
From 29.00€
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