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Item number: Cay35898-1

11alpha-Hydroxyprogesterone (11alpha-OHP) is an inhibitor of 11beta-hydroxysteroid dehydrogenase (IC50s = 0.63 and 0.4 µM for recombinant human 11beta-HSD1 and 11beta-HSD2, respectively) and a derivative of the endogenous hormone progesterone (Cay-15876). 11alpha-OHP (10, 100, and 500 µg/animal) reduces urinary...

Keywords:	11alpha-OHP, NSC 3350, U-0384, 11alpha-hydroxy-pregn-4-ene-3,20-dione
Application:	11-HSD inhibitor, progesterone derivative
CAS	80-75-1
MW:	330.5 D

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11alpha-Hydroxyprogesterone

Item number: TGM-T84842-10mg

Description: 11alpha-Hydroxyprogesterone, an inactive analogue of 11beta-Hydroxyprogesterone, serves as an experimental control. Meanwhile, 11beta-Hydroxyprogesterone functions as a potent inhibitor of 11beta-Hydroxysteroid dehydrogenase and activates the human mineralocorticoid receptor in COS-7 cells, with an...

Application:	11-HSD inhibitor, progesterone derivative
CAS	80-75-1
MW:	330.468 D

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