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Simvastatin
Simvastatin

Item number: Cay10010344-5

Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki = 0.12 nM). Simvastatin reduces plasma cholesterol levels in rats and dogs when administered at doses of 1.2 and 8 mg/kg, respectively. Simvastatin suppresses TNF-induced NF-kappaB activation (IC50 = ~13 µM) and potentiates apoptosis in human myeloid...
Keywords: MK-733,...
Application: HMG-CoA reductase inhibitor
CAS 79902-63-9
MW: 418.6 D
From 43.00€ *
Review
Simvastatin
Simvastatin

Item number: AG-CN2-0052-M010

Synthetic analog of Lovastatin (Prod. No. AG-CN2-0051), potent competitive HMG-CoA reductase inhibitor, anti-hypercholesterolemic agent, cholesterol/isoprenoid biosynthesis inhibitor. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids, inhibits the...
Keywords: MK-733, Synvinolin, BRN 4768038
Application: NF-kappaB activation inhibitor
CAS 79902-63-9
MW: 495,7 D
From 28.00€ *
Review
Simvastatin
Simvastatin

Item number: LKT-S3449.500

Statin, HMG-CoA reductase inhibitor, potential ATP-sensitive K+ channel activator, L-type Ca2+ channel blocker.
Keywords: Synvinolin, MK-733, Denan, Liponorm, Lodales, Simovil, Sinvacor, Sivastin, Zocor, Zocord, 2,2-Dimethylbutanoic acid...
Application: HMG-CoA reductase inhibitor
CAS 79902-63-9
MW: 418,57 D
From 86.00€ *
Review