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beta-Secretase Inhibitor IV
Item number: Cay23388-500
beta-Secretase inhibitor IV is an inhibitor of beta-site amyloid protein cleaving enzymes (BACE/beta-secretase) 1 and 2 (IC50s = 15 and 230 nM for human BACE1 and 2, respectively). It has >500-fold selectivity for BACE1 and 2 over the aspartyl proteases renin and cathepsin D. beta-Secretase inhibitor IV inhibits...
| Keywords: | N1-[(1S,2R)-3-(cyclopropylamino)-2-hydroxy-1-(phenylmethyl)propyl]-5-[methyl(methylsulfonyl)amino]-N3-[(1R)-1-phenylethyl]... |
| Application: | Beta-secretase inhibitor |
| CAS | 797035-11-1 |
| MW: | 578.7 D |
From 206.00€
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beta-Secretase Inhibitor IV
Item number: TGM-T13434-1mg
Description: beta-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1, with IC50 values of 15.6 nM and 16.3 nM at BACE-1 concentrations of 2 nM and 100 pM, respectively. Target: Others. Smiles: C(N[C@@H](CC1=CC=CC=C1)[C@@H](CNC2CC2)O)(=O)C3=CC(C(N[C@H](C)C4=CC=CC=C4)=O)=CC(N(S(C)(=O)=O)C)=C3....
| Application: | beta-Secretase inhibitor |
| CAS | 797035-11-1 |
| MW: | 578.72 D |
From 458.00€
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