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20-hydroxy Leukotriene B4
20-hydroxy Leukotriene B4

Item number: Cay20190-25

20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. 20-hydroxy LTB4 is not only much less active (~5%) compared to LTB4 in causing degranulation of PMNL, but actually inhibits LTB4-induced degranulation of human neutrophils (Ki =...
Keywords: 20-hydroxy LTB4, 5S,12R,20-trihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 79516-82-8
MW: 352.5 D
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