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SB-334867
Item number: Cay19145-1
SB-334867 is an antagonist of the orexin 1 receptor (OX1R, KB = 39.8 nM) that is selective for OX1R over OX2R (KB = 1,995.3 nM). It reduces food intake and increases resting duration in rats, as well as inhibits orexin-A-induced increases in food intake, when administered at a dose of 30 mg/kg. SB-334867 (10 mg/kg)...
| Keywords: | N-(2-methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl-urea |
| Application: | OX1 receptor antagonist |
| CAS | 792173-99-0 |
| MW: | 319.3 D |
From 40.00€
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SB-334867 free base
Item number: TGM-T6140-100mg
Description: SB-334867 free base (SB334867A free base) is a selective antagonist of the orexin-1 (OX1) receptor. Target: OX Receptor. Smiles: N(C(NC=1C=C2C(=CC1)N=C(C)O2)=O)C=3C4=C(N=CC3)C=CC=N4. References: Smart D, et al. Br J Pharmacol. 2001, 132(6), 1179-1182.
| Keywords: | SB334867A free base , SB-334867 , SB 334867 , SB334867 |
| Application: | OX1 receptor antagonist |
| CAS | 792173-99-0 |
| MW: | 319.32 D |
From 34.00€
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