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VU0119498

Item number: Cay36132-100

VU0119498 is a positive allosteric modulator (PAM) of M1, M3, and M5 muscarinic acetylcholine receptors (mAChRs, EC50s = 6.04, 6.38, and 4.08 µM, respectively, in calcium mobilization assays). It is selective for M1, M3, and M5 mAChRs over M2 and M4 mAChRs in CHO cells expressing the human receptors. VU0119498 (20...

Keywords:	1-[(4-bromophenyl)methyl]-1H-indole-2,3-dione
Application:	Muscarinic acetylcholine receptor M1 / M3 / M5 positive allosteric modulator
CAS	79183-37-2
MW:	316.2 D

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