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VU0119498
VU0119498

Item number: TGM-T8224-100mg

Description: VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 µM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent. Target: AChR. Smiles: Brc1ccc(CN2C(=O)C(=O)c3ccccc23)cc1. References: Lu Zhu , Mario Rossi,et al.Allosteric Modulation of beta-Cell M 3 Muscarinic...
Application: Muscarinic acetylcholine receptor M1 / M3 / M5 positive allosteric modulator
CAS 79183-37-2
MW: 316.15 D
From 31.00€ *
Review
VU0119498
VU0119498

Item number: Cay36132-100

VU0119498 is a positive allosteric modulator (PAM) of M1, M3, and M5 muscarinic acetylcholine receptors (mAChRs, EC50s = 6.04, 6.38, and 4.08 µM, respectively, in calcium mobilization assays). It is selective for M1, M3, and M5 mAChRs over M2 and M4 mAChRs in CHO cells expressing the human receptors. VU0119498 (20...
Keywords: 1-[(4-bromophenyl)methyl]-1H-indole-2,3-dione
Application: Muscarinic acetylcholine receptor M1 / M3 / M5 positive allosteric modulator
CAS 79183-37-2
MW: 316.2 D
From 78.00€ *
Review