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Item number: Cay37712-1

DMHCA is a liver X receptor (LXR) agonist. It activates LXRalpha and LXRbeta in CV-1 cells expressing the human receptors in reporter assays (EC50 = 2 µM for both). DMHCA also inhibits ?24-dehydrocholesterol reductase (DHCR24, IC50 = 0.7 nM). It does not induce steatosis or increase liver triglyceride levels...

Keywords:	Dimethyl-HCA, N,N-Dimethyl-3beta-hydroxycholenamide, (3beta)-3-hydroxy-N,N-dimethyl-chol-5-en-24-amide
Application:	LXR agonist
CAS	79066-03-8
MW:	401.6 D

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