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Item number: Cay34102-10

Mofezolac is an inhibitor of COX-1 (IC50 = 14 nM). It is selective for COX-1 over COX-2 (IC50 = 440 nM). Mofezolac (1 µg/ml) protects against LPS-induced cell death in BV-2 microglia. In vivo, mofezolac (6 mg/kg, i.p.) reduces hippocampal microglial activation and prostaglandin E2 (PGE2, Cay-14010) production in a...

Keywords:	N-22, 3,4-bis(4-methoxyphenyl)-5-isoxazoleacetic acid
Application:	COX-1 inhibitor
CAS	78967-07-4
MW:	339.3 D

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