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AFP 07 (free acid)
Item number: Cay13626-1
Prostaglandin I2 is an unstable prostanoid which, through the 'I prostanoid' (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds. AFP 07 is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor (Ki = 0.561 nM). AFP...
| Keywords: | 5Z-[(3aR,4R,5R,6aS)-3,3-difluorohexahydro-5-hydroxy-4-[(1E,3S,4S)-3-hydroxy-4-methyl-1-nonen-6-ynyl]-2H-cyclopenta[b]furan... |
| Application: | IP receptor agonist |
| CAS | 788799-13-3 |
| MW: | 412.5 D |
From 184.00€
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AFP-07 free acid
Item number: TGM-T23657L-1mg
Description: AFP 07 free acid is a 7,7-difluoroprostacyclin derivative. It also acts as a selective and highly potent agonist for the IP receptor. Target: Others. Smiles: C(=C/[C@H]([C@H](CC#CCC)C)O)\[C@@H]1[C@@]2([C@@](O/C(=C\CCCC(O)=O)/C2(F)F)(C[C@H]1O)[H])[H]. References: McCormick C, Jones RL, Kennedy S,...
| CAS | 788799-13-3 |
| MW: | 412.47 D |
From 402.00€
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