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Item number: Cay32819-10

MLN120B is an inhibitor of IkappaB kinase beta (IKKbeta, IC50 = 45 nM). It is selective for IKKbeta over a panel of 30 tyrosine and serine/threonine kinases (IC50s = >50 µM for all). MLN120B inhibits NF-kappaB activation induced by phorbol 12-myristate 13-acetate (TPA, Cay-10008014) with an IC50 value of 2.8 µM in a...

Keywords:	(9CI, ACI)-N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methyl-3-pyridinecarboxamide
Application:	IKKbeta inhibitor
CAS	783348-36-7
MW:	366.8 D

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MLN120B

Item number: TGM-TQ0306-100mg

Description: MLN120B is a selective and ATP competitive IKKbeta inhibitor (IC50: 60 nM). Target: IkappaB/IKK. Smiles: COc1c(Cl)cc2c3ccncc3[nH]c2c1NC(=O)c1cccnc1C. References: Hideshima T, et all. MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo. Clin Cancer...

Application:	IKKbeta inhibitor
CAS	783348-36-7
MW:	366.8 D

From 43.00€ *

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