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Item number: Cay34607-1

7-ethyl Camptothecin is a derivative of camptothecin (Cay-11694) and an anticancer agent. It inhibits wild-type but not Gly533 mutant topoisomerase I in RPMI-8402 and CPT-K5 cells, respectively (IC50s = 5.48 and >2,500 nM, respectively). 7-ethyl Camptothecin is cytotoxic to ADJ/PC6 SN-38-sensitive and PC6/SN2-5H2...

Keywords:	SN-22, (4S)-4,11-diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Application:	Anticancer agent, TOP1 inhibitor
CAS	78287-27-1
MW:	376.4 D

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