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Item number: Cay40986-10

Bisantrene is an inhibitor of fat mass and obesity-associated protein (FTO, IC50 = 142.6 nM in a cell-free assay). It decreases the viability of Mono-Mac-6, NOMO-1, U937, MV4-11, and ML-2 acute myeloid leukemia (AML) cells (IC50s = 58.9-175.9 nM), as well as increases the levels of N6-methyladenosine (m6A) in...

Keywords:	Bisantrenum, 9,10-bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone] 9,10-anthracenedicarboxaldehyde
Application:	FTO inhibitor, antineoplastic
CAS	78186-34-2
MW:	398.5 D

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Bisantrene

Item number: TGM-T4047-100mg

Description: Bisantrene (CL216942) is an anthracenyl bishydrazone with antineoplastic activity. Bisantrene intercalates with and disrupts the configuration of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and inhibition of DNA replication. This agent is similar to doxorubicin in activity, but...

Keywords:	CL216942
Application:	FTO inhibitor, antineoplastic
CAS	78186-34-2
MW:	398.46 D

From 34.00€ *

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