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Item number: Cay20918-1

Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 µM), which is an enzyme involved in the biosynthesis of cholesterol. It has antitumor properties, such as decreasing proliferation and inducing apoptosis in many cancer cell lines and slowing tumor growth in a mouse xenograft model. It...

Keywords:	MER-29, NSC 65345, 4-chloro-alpha-[4-[2-(diethylamino)ethoxy]phenyl]-alpha-(4-methylphenyl)-benzeneethanol
Application:	Delta(24)-sterol reductase inhibitor
CAS	78-41-1
MW:	438 D

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Triparanol

Item number: TGM-T26296-10mg

Description: Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparanol suppresses human tumor growth and is an antilipemic agent with high ophthalmic...

Keywords:	MER-29, NSC 65345, NSC65345, NSC-65345
CAS	78-41-1
MW:	438 D

From 281.00€ *

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