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Item number: Cay12095-1

Gcn5 is a chromatin modifying factor whose HAT activity is required to acetylate histone H3 lysine 9 (K9) and K14, which facilitates transcription elongation by relaxing nucleosomes. Butyrolactone 3 specifically inhibits the histone acetyltransferase Gcn5 with an IC50 value of 100 µM and has an affinity to the Gcn5...

Keywords:	rel-tetrahydro-4-methylene-5-oxo-2R-propyl-3S-furancarboxylic acid
Application:	HAT inhibitor
CAS	778649-18-6
MW:	184.2 D

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Butyrolactone 3

Item number: AG-CR1-3522-M002

Specific histone acetyltransferase Gcn5 inhibitor. Anticancer compound. Pre-mRNA splicing inhibitor. Blocks splicing before the first catalytic steps. Potential anti-inflammatory compound.

Keywords:	(2R,3S)-rel-Tetrahydro-4-methylene-5-oxo-2-propyl-3-furancarboxylic acid, MB-3
Application:	Histone acetyltransferase Gcn5 inhibitor
CAS	778649-18-6
MW:	184 D

105.00€ *

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