Description: Anecortave Acetate (NSC-24345), an angiostatic steroid, is used for proteomics research. Target: Others. Smiles: C[C@@]12[C@]([C@]3(C([C@]4(C)C(CC3)=CC(=O)CC4)=CC1)[H])(CC[C@@]2(C(COC(C)=O)=O)O)[H]. References: Shepard AR, Conrow RE, Pang IH, Jacobson N, Rezwan M, Rutschmann K, Auerbach D, Sriramaratnam...

Anecortave acetate is a sterol lipid. It inhibits VEGF-induced increases in vascular generation, number, and length in isolated rat retinas when used at a concentration of 1 µM. Sub-tenon administration of anecortave acetate (7.5% w/v) prevents and reduces increases in intraocular pressure induced by prednisolone...