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Item number: Cay42034-1

A P2X4 receptor antagonist (IC50 = 0.75 µM), selective for P2X4 over P2X1, P2X2a, P2X2b, and P2X7 but does inhibit P2X3 by 35.9% at 10 µM, decreases fEPSP slopes in rat hippocampal slices at 10 µM, inhibits nitroglycerin-induced mechanical hyperalgesia in a mouse model of chronic migraine at 28 mg/kg, decreases...

Keywords:	5-(3-bromophenyl)-1,3-dihydro-2H-benzofuro[3,2-e]-1,4-diazepin-2-one
Application:	P2X4 receptor antagonist
CAS	768404-03-1
MW:	355.2 D

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5-BDBD

Item number: TGM-T22518-100mg

Description: 5-BDBD is a potent and selective P2X4 receptor antagonist. 5-BDBD inhibits rP2X4R-mediated currents with an IC50 of 0.75 µM. 5-BDBD completely blocked the basal and acute hyperalgesia induced by NTG. Target: P2X Receptor. Smiles: Brc1cccc(c1)C1=NCC(=O)Nc2c1oc1ccccc21. References: Coddou C, et al....

CAS	768404-03-1
MW:	355.19 D

From 35.00€ *

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