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AVE-1231
Item number: Cay45299-1
An inhibitor of K2P3.1/TASK1, reduces potassium currents in X. laevis oocytes expressing TASK1 or Kv1.5 (IC50s = 0.22 and 5.6 µM, respectively), restores sinus rhythm in a porcine model of acute paroxysmal atrial fibrillation at 1 mg/kg, reduces the severity of EAE in wild-type mice but not TASK1 knockout mice at...
| Keywords: | A293, 2-[(butylsulfonyl)amino]-N-[(1R)-1-(6-methoxy-3-pyridinyl)propyl]-benzamide |
| Application: | K2P3.1/TASK1 inhibitor |
| CAS | 767334-89-4 |
| MW: | 405.51 D |
From 416.00€
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AVE1231
Item number: TGM-T68730-100mg
Description: AVE1231 is a TASK-1 channel blocker that inhibits TASK-1 and can be used in the study of atrial fibrillation. Target: Potassium Channel. Smiles: N(S(CCCC)(=O)=O)C1=C(C(N[C@H](CC)C=2C=CC(OC)=NC2)=O)C=CC=C1. References: Wiedmann F, et al. Identification of the A293 (AVE1231) Binding Site in the Cardiac...
| CAS | 767334-89-4 |
| MW: | 405.51 D |
From 149.00€
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