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KU-0058948
KU-0058948

Item number: TGM-T68736-100mg

Description: KU-0058948 is a poly (ADP-ribose) polymerase (PARP) inhibitor that induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro. Target: Others. Smiles: C(C=1C=2C(C(=O)NN1)=CC=CC2)C3=CC(C(=O)N4CCCNCC4)=C(F)C=C3
CAS 763111-49-5
MW: 380.42 D
From 1,440.00€ *
Review
KU-0058948
KU-0058948

Item number: Cay42098-1

A PARP1 and PARP2 inhibitor (IC50s = 3.4 and 1.5 nM, respectively), selective for PARP1 over PARP3, PARP4, and tankyrase (IC50s = 40, 1,200, and >10,000 nM, respectively), selectively inhibits the survival of embryonic stem cells lacking Brca1 or Brca2 over embryonic stem cells expressing wild-type Brca1 or Brca2,...
Keywords: 4-[[4-fluoro-3-[(hexahydro-1H-1,4-diazepin-1-yl)carbonyl]phenyl]methyl]-1(2H)-phthalazinone
Application: PARP1 / PARP2 inhibitor
CAS 763111-49-5
MW: 380.4 D
From 60.00€ *
Review