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Leflunomide
Item number: Cay14860-25
Leflunomide is a synthetic isoxazol and a prodrug form of A-771726 (Cay-14404), a dihydroorotate dehydrogenase inhibitor. Leflunomide inhibits de novo pyrimidine synthesis to regulate T lymphocyte progression through the cell cycle. It inhibits proliferation and activation of T cells when used at concentrations of...
| Keywords: | Arava, HW 486, SU 101, 5-methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide |
| Application: | Immunosuppressant, pyrimidine synthesis inhibitor, dihydroorotate dehydrogenase inhibitor |
| CAS | 75706-12-6 |
| MW: | 270.2 D |
From 49.00€
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Leflunomide
Item number: LKT-L1817.1
Leflunomide is a pyrimidine biosynthesis inhibitor. It is an established disease-modifying antirheumatic drug. It has been approved for treatment of rheumatoid arthritis (RA) and may also be useful in treating patients with Felty´s syndrome. It is suggested that supression of TNF signalling is one of the...
| Keywords: | HWA-486 |
| Application: | Pyrimidine biosynthesis inhibitor |
| CAS | 75706-12-6 |
| MW: | 270,21 D |
From 141.00€
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Leflunomide
Item number: TGM-T1159-100mg
Description: Leflunomide (HWA486) is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis. Target: Others, AhR, Dehydrogenase. Smiles: CC1=C(C=NO1)C(=O)NC1=CC=C(C=C1)C(F)(F)F. References: Davis JP, et al. Biochemistry, 1996, 35(4), 1270-1273.
| Keywords: | SU101, HWA486, RS-34821 |
| CAS | 75706-12-6 |
| MW: | 270.21 D |
From 38.00€
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