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Migalastat hydrochloride
Migalastat hydrochloride

Item number: TGM-T12038-1mg

Description: Migalastat hydrochloride (GR181413A) is an orally available, potent and competitive inhibitor of alpha-galactosidase A. It promotes the transport of alpha-galactosidase A to the lysosome and can be used in the study of Fabry disease. Target: Others. Smiles: Cl.OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O....
Keywords: GR181413A HCl, Migalastat HCl, GR181413A hydrochloride
Application: Targets alpha-galactosidase [EC:3.2.1.22] (GLA)
CAS 75172-81-5
MW: 199.63 D
31.00€ *
Review
1-Deoxygalactonojirimycin (hydrochloride)
1-Deoxygalactonojirimycin (hydrochloride)

Item number: Cay17179-5

1-Deoxygalactonojirimycin is a competititve inhibitor of alpha-galactosidase (IC50 = 40 nM). At subinhibitory concentrations, 1-Deoxygalactonojirimycin binds to alpha-galactosidase and chaperones unstable enzyme variants through the endoplasmic reticulum, allowing its movement into lysosomes. Pharmacological...
Keywords: DGJ, Migalastat, (2R,3S,4R,5S)-2-(hydroxymethyl)-3,4,5-piperidinetriol, monohydrochloride
Application: alpha-galactosidase inhibitor
CAS 75172-81-5
MW: 199.6 D
From 53.00€ *
Review