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Item number: Cay15036-1

JSH-23 is an inhibitor of NF-kappaB, blocking its translocation into the nucleus (IC50 = 7.1 µM). It does not affect degradation of the inhibitor of NF-kappaB, IkappaB. JSH-23 interferes with NF-kappaB-mediated gene expression and apoptosis in RAW 264.7 cells treated with lipopolysaccharide. It has also been used to...

Keywords:	NF-kappaB Activation Inhibitor II, 4-methyl-N1-(3-phenylpropyl)-1,2-benzenediamine
Application:	NFkappaB inhibitor
CAS	749886-87-1
MW:	240.3 D

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