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VER-50589
VER-50589

Item number: Cay13132-1

The heat shock proteins (Hsps) act as molecular chaperones. Hsp90 is an abundant protein with roles in protein folding, cell signaling, and cancer. VER-50589 is an isoxazole compound that inhibits Hsp90 with an IC50 value of 21 nM. It produces a mean cellular antiproliferative GI50 value of 78 nM when tested against...
Keywords: 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-3-isoxazolecarboxamide
Application: Hsp90 inhibitor
CAS 747413-08-7
MW: 388.8 D
From 67.00€ *
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VER-50589
VER-50589

Item number: TGM-T2258-100mg

Description: VER-50589 is a potent HSP90 inhibitor. Target: Apoptosis, HSP. Smiles: CCNC(=O)c1noc(c1-c1ccc(OC)cc1)-c1cc(Cl)c(O)cc1O. References: Sharp SY, et al. Mol Cancer Ther. 2007, 6(4), 1198-1211.
Keywords: VER50589
Application: Hsp90 inhibitor
CAS 747413-08-7
MW: 388.8 D
From 46.00€ *
Review