Description: Rubiadin-1-methyl ether (Rubiadin 1-methyl ether) is a natural product.It inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-kappaB p65 and the degradation of IkappaBalpha as well as decrease in the nuclear translocation of p65. Target: Anti-infection, NF-kappaB. Smiles:...

Rubiadin-1 methyl ether is an anthraquinone that has been found in Heterophyllaea pustulata and has diverse biological activities. It generates superoxide radicals in isolated human neutrophils and monocytes when used at a concentration of 20 µg/ml, an effect that can be enhanced by UV radiation. Rubiadin-1 methyl...