1-Deoxymannojirimycin is a specific inhibitor of class I alpha-1,2-mannosidase (IC50 = 0.02 µM), a key enzyme for N-glycan processing in the endoplasmic reticulum and Golgi and for targeting misfolded proteins for translocation out of the endoplasmic reticulum and degradation by the proteasome. By inhibiting...

Description: 1-Deoxymannojirimycin hydrochloride, a selective alpha1,2-mannosidase inhibitor (IC50: 20 µM), also inhibits HIV-1 strains but exhibits poor antiviral activity. Target: HIV Protease, Influenza Virus, Others. Smiles: Cl.OC[C@H]1NC[C@@H](O)[C@@H](O)[C@@H]1O. References: Jan Balzarini, et al. The...