2 products were found matching "733750-99-7"!
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AR 231453
Item number: TGM-T8329-100mg
Description: AR 231453 is a selective and orally available GPR119 agonist,can stimulate beta-cell replication and improve islet graft function. Target: GPR. Smiles: N(=O)(=O)C=1C(=NC=NC1NC2=C(F)C=C(S(C)(=O)=O)C=C2)N3CCC(CC3)C4=NC(C(C)C)=NO4. References: Chu ZL, et al. A role for intestinal endocrine cell-expressed g...
| Application: | GPR119 agonist |
| CAS | 733750-99-7 |
| MW: | 505.52 D |
From 31.00€
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AR231453
Item number: Cay34898-10
AR231453 is an agonist of GPR119. It increases cAMP accumulation in HIT-T15 beta cells that endogenously express high levels of GPR119 (EC50 = 4.7 nM). AR231453 increases insulin release from HIT-T15 cells (EC50 = 3.5 nM) and increases glucose-induced insulin release in isolated rat and mouse islets. It reduces...
| Keywords: | N-[2-fluoro-4-(methylsulfonyl)phenyl]-6-[4-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-5-nitro-4-pyrimidinamine |
| Application: | GPR119 agonist |
| CAS | 733750-99-7 |
| MW: | 505.5 D |
From 128.00€
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