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ITF 2357
ITF 2357

Item number: Cay11045-1

ITF 2357 inhibits class I and class II histone deacetylases (maize HDACs: HD2, HD-1B, and HD-1A with IC50s = 7.5-16 nM) and reduces the production of several pro-inflammatory cytokines including TNFalpha, IL-1alpha, and IL-1beta (IC50s = 10-22 nM). ITF 2357 also has activity against cells expressing janus kinase 2...
Keywords: N-[4-[(hydroxyamino)carbonyl]phenyl]-carbamic acid, [6-[(diethylamino)methyl]-2-naphthalenyl]methyl ester,...
Application: HDAC inhibitor
CAS 732302-99-7
MW: 476 D
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