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Item number: TGM-T21758-100mg

Description: Calindol hydrochloride is a potent orthosteric modulator (EC50: 132 nM) of the putative calcium-calcium-sensitive receptor (CaSR), inhibits Pi-induced VC, and delays the progression of calcification in vascular smooth muscle cells. Target: CaSR. Smiles: Cl.C[C@@H](NCc1cc2ccccc2[nH]1)c1cccc2ccccc12....

CAS	729610-18-8
MW:	336.86 D

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Calindol (hydrochloride)

Item number: Cay17575-5

Calindol is a phenylalkylamine calcimimetic that facilitates the activation of the calcium-sensing receptor (CaSR), a G protein-coupled receptor that triggers phosphatidylinositol (PI)-intracellular calcium signaling and, in some cell types, cell proliferation. It potently stimulates PI hydrolysis and proliferation...

Keywords:	N-[(1R)-1-(1-naphthalenyl)ethyl]-1H-indole-2-methanamine, monohydrochloride
Application:	Calcimimetic
CAS	729610-18-8
MW:	336.9 D

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