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Item number: Cay14858-10

MIRA-1 is a maleimide-derived small molecule that reactivates the tumor suppressor function of mutant p53, inducing apoptosis in several human solid tumor cell lines carrying tetracycline-regulated mutant p53 (IC50 = 10 µM in vitro). Treatment of tumor cells with MIRA-1 induces p21, MDM2 and PUMA in a mutant...

Keywords:	NSC 19630, 1-[(1-oxopropoxy)methyl]-1H-pyrrole-2,5-dione
Application:	Mutant p53 tumor suppressor function reactivator
CAS	72835-26-8
MW:	183.2 D

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