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Item number: Cay28103-5

Diflapolin is a dual inhibitor of 5-lipoxygenase-activating protein (FLAP) and soluble epoxide hydrolase (sEH). It inhibits formation of the 5-lipoxygenase (5-LO) products leukotriene B4 (LTB4, Cay-20110) and 5-HpETE (Cay-44230) in isolated human monocytes and neutrophils (IC50s = 30 and 170 nM, respectively) and...

Keywords:	N-[4-(2-benzothiazolylmethoxy)-2-methylphenyl]-N'-(3,4-dichlorophenyl)-urea
Application:	5-lipoxygenase-activating protein (FLAP) inhibitor, soluble epoxide hydrolase (sEH) inhibitor
CAS	724453-98-9
MW:	458.4 D

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