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Item number: TGM-T8844-100mg

Description: Diflapolin is a highly active dual 5-lipoxygenase-activating protein (FLAP) and soluble epoxide hydrolase (sEH) inhibitor, exhibiting marked anti-inflammatory efficacy and high target selectivity. Target: Others, Epoxide Hydrolase, FLAP. Smiles: Cc1cc(OCc2nc3ccccc3s2)ccc1NC(=O)Nc1ccc(Cl)c(Cl)c1....

Application:	5-lipoxygenase-activating protein (FLAP) inhibitor, soluble epoxide hydrolase (sEH) inhibitor
CAS	724453-98-9
MW:	458.36 D

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Diflapolin

Item number: Cay28103-5

Diflapolin is a dual inhibitor of 5-lipoxygenase-activating protein (FLAP) and soluble epoxide hydrolase (sEH). It inhibits formation of the 5-lipoxygenase (5-LO) products leukotriene B4 (LTB4, Cay-20110) and 5-HpETE (Cay-44230) in isolated human monocytes and neutrophils (IC50s = 30 and 170 nM, respectively) and...

Keywords:	N-[4-(2-benzothiazolylmethoxy)-2-methylphenyl]-N'-(3,4-dichlorophenyl)-urea
Application:	5-lipoxygenase-activating protein (FLAP) inhibitor, soluble epoxide hydrolase (sEH) inhibitor
CAS	724453-98-9
MW:	458.4 D

From 65.00€ *

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