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Item number: Cay19205-1

VAS2870 is a selective inhibitor of the NADPH oxidases. Pre-incubation of rat vascular smooth muscle cells with VAS2870 abolishes platelet-derived growth factor-dependent chemotaxis without affecting cell cycle progression (IC50 = 10 µM). At low (2.8 mM), but not high (16.7 mM), concentrations of glucose, treatment...

Keywords:	7-(2-benzoxazolylthio)-3-(phenylmethyl)-3H-1,2,3-triazolo[4,5-d]pyrimidine
Application:	Cell-permeable specific NADPH oxidase inhibitor
CAS	722456-31-7
MW:	360.4 D

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VAS2870

Item number: TGM-T4359-100mg

Description: VAS2870 is an inhibitor of NADPH oxidase (NOX). Target: NADPH. Smiles: C(c1ccccc1)n1nnc2c(Sc3nc4ccccc4o3)ncnc12. References: ten Freyhaus H, et al. Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation. Cardiovasc Res. 2006 Jul 15,71(2):331-41.

Application:	Cell-permeable specific NADPH oxidase inhibitor
CAS	722456-31-7
MW:	360.39 D

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