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TG007
TG007

Item number: AG-CR1-3666-M005

White to off-white solid. Soluble in DMSO (10mg/ml). Prodrug form (acetylated derivative) of INDY (Prod. No. AG-CR1-3665), Cell permeable ATP-competitive DYRK1A and DYRK1B inhibitor, Inhibits phosphorylation of Tau-protein and rescues repressed calcineurin/NFAT signaling, Recovers Xenopus embryos from head...
Keywords: (Z)-3-Ethyl-2-(2-oxopropylidene)-2,3-dihydrobenzo[d]thiazol-5-yl acetate, ProINDY
Application: Cell permeable ATP-competitive DYRK1A / DYRK1B inhibitor prodrug
CAS 719277-30-2
MW: 277,3 D
88.00€ *
Review
ProINDY
ProINDY

Item number: TGM-T23186-100mg

Description: ProINDY (Pro-indy) is a potent DYRK inhibitor that activates NFAT for the study of Down syndrome. Target: DYRK. Smiles: CCN1\C(Sc2ccc(OC(C)=O)cc12)=C\C(C)=O. References: Lee TD, et al. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Mol Pharmacol....
Keywords: Pro-indy
Application: Cell permeable ATP-competitive DYRK1A / DYRK1B inhibitor prodrug
CAS 719277-30-2
MW: 277.34 D
From 86.00€ *
Review