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Item number: TGM-T2113-100mg

Description: PHA-793887 has been used in trials studying the treatment of Advanced/Metastatic Solid Tumors. Target: CDK, Apoptosis. Smiles: CC(C)CC(=O)Nc1n[nH]c2c1CN(C(=O)C1CCN(C)CC1)C2(C)C. References: Brasca MG, et al. Bioorg Med Chem, 2010, 18(5), 1844-1853.

Keywords:	PHA 793887, PHA793887
Application:	CDK2, CDK5, CDK7 inhibitor
CAS	718630-59-2
MW:	361.48 D

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PHA-793887

Item number: Cay18388-5

PHA-793887 is an inhibitor of cyclin-dependent kinases (CDKs, IC50s = 8, 8, 5, and 10 nM for Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and Cdk7/cyclin H, respectively). It is selective for these CDKs over Cdk1/cyclin B, Cdk4/cyclin D1, Cdk9/cyclin T1, and glycogen synthase kinase 3beta (GSK3beta, IC50s = 60, 62, 138,...

Keywords:	3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]-butanamide
Application:	CDK2, CDK5, CDK7 inhibitor
CAS	718630-59-2
MW:	361.5 D

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