2 products were found matching "717824-30-1"!

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Item number: Cay18377-10

Dihydroorotate dehydrogenase (DHODH) is involved in pyrimidine nucleoside biosynthesis. DHODH inhibitors have value in autoimmune diseases as well as cancer and certain infections. Vidofludimus is an immunosuppressive drug that inhibits DHODH (IC50s = 0.134, 1.29, and 10.6 µM for human, rat, and mouse isoforms,...

Keywords:	4SC-101, 2-[[(3-fluoro-3'-methoxy[1,1'-biphenyl]-4-yl)amino]carbonyl]-1-cyclopentene-1-carboxylic acid
Application:	Dihydroorotate dehydrogenase (DHODH) inhibitor
CAS	717824-30-1
MW:	355.4 D

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Vidofludimus

Item number: TGM-T2601-100mg

Description: Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH). Target: DNA/RNA Synthesis, Dehydrogenase, Interleukin. Smiles: COc1cccc(c1)-c1ccc(NC(=O)C2=C(CCC2)C(O)=O)c(F)c1. References: Kulkarni OP, et al. Am J Pathol. 2010, 176(6), 2840-2847.

Keywords:	4sc-101, SC12267
Application:	Dihydroorotate dehydrogenase (DHODH) inhibitor
CAS	717824-30-1
MW:	355.36 D

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