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Item number: Cay15184-1

ML-193 is a potent antagonist of GPR55 (IC50 = 221 nM). It displays selectivity for GPR55 over CB1, CB2, and GPR35. ML-193 inhibits GPR55-dependent ERK phosphorylation (IC50 = 65 nM) and blocks translocation of PKCbetaII. ML-193 blocks increases in intracellular calcium levels induced by lysophosphatidylinositol...

Keywords:	CID-1261822, N-[4-[[(3,4-dimethyl-5-isoxazolyl)amino]sulfonyl]phenyl]-6,8-dimethyl-2-(2-pyridinyl)-4-quinolinecarboxamide
Application:	Potent GPR55 antagonist
CAS	713121-80-3
MW:	527.6 D

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ML-193

Item number: TGM-T22103-100mg

Description: ML-193 (CID 1261822) is a potent and selective GPR55 antagonist (IC50: 221 nM) with over 27-fold selectivity for GPR55 over GPR35, CB1, and CB2. It can ameliorate motor and sensorimotor deficits in Parkinson's disease (PD) rats. Target: Cannabinoid Receptor. Smiles:...

Keywords:	CID 1261822
CAS	713121-80-3
MW:	527.59 D

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