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SirReal2
Item number: TGM-T6984-100mg
Description: SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM. Target: Sirtuin. Smiles: Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc4ccccc34)s2)n1. References: Rumpf T, et al. Nat Commun. 2015, 6, 6263.
| Application: | SIRT2 inhibitor |
| CAS | 709002-46-0 |
| MW: | 420.55 D |
From 34.00€
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SirReal2
Item number: Cay18116-1
Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). SIRT2 deacetylates histone H4 and alpha-tubulin and functions as a regulator of cell cycle progression, a determinant of myelination, a modulator of autophagy, and a suppressor of brain inflammation....
| Keywords: | 2-[(4,6-dimethyl-2-pyrimidinyl)thio]-N-[5-(1-naphthalenylmethyl)-2-thiazolyl]-acetamide |
| Application: | SIRT2 inhibitor |
| CAS | 709002-46-0 |
| MW: | 420.5 D |
From 52.00€
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