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JNJ-10397049
JNJ-10397049

Item number: Cay14139-1

JNJ-10397049 is a potent, selective, and bioavailable antagonist of the orexin-2 receptor (OX2R) (KB = 4.5 nM for OX2R versus 1.1 µM for OX1R). It has no significant affinity for over 50 other neurotransmitters or neuropeptide receptors. Applied subcutaneously to rats, JNJ-10397049 decreases the latency to...
Keywords: N-(2,4-dibromophenyl)-N'-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]-urea
Application: Orexin receptor type 2 (Ox2R) antagonist
CAS 708275-58-5
MW: 484.2 D
From 67.00€ *
Review
JNJ-10397049
JNJ-10397049

Item number: TGM-T22880-2mg

Description: OX2 receptor antagonist. Target: Others. Smiles: CC1(C)OC[C@H](NC(=O)Nc2ccc(Br)cc2Br)[C@@H](O1)c1ccccc1
Keywords: JNJ 10397049
Application: Orexin receptor type 2 (Ox2R) antagonist
CAS 708275-58-5
MW: 484.18 D
86.00€ *
Review