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Cytarabine 5'-monophosphate
Cytarabine 5'-monophosphate

Item number: Cay36496-5

Cytarabine 5'-monophosphate (ara-CMP) is an active metabolite of the nucleoside analog cytarabine (Cay-16069). It is formed from cytarabine by deoxycytidine kinase. ara-CMP is incorporated into DNA by DNA polymerase alpha, which slows the rate of DNA synthesis by approximately 2,000-fold in a cell-free assay. It...
Keywords: 1-beta-D-Arabinofuranosylcytosine 5'-monophosphate, ara-CMP, Cytosine Arabinoside monophosphate, NSC 99445,...
Application: Cytarabine active metabolite
CAS 7075-11-8
MW: 323.2 D
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Cytarabine 5'-monophosphate
Cytarabine 5'-monophosphate

Item number: TGM-T84932-10mg

Description: Cytarabine 5'-monophosphate (ara-CMP), an active metabolite of the nucleoside analog cytarabine formed by deoxycytidine kinase, is incorporated into DNA by DNA polymerase alpha, significantly slowing DNA synthesis. It inhibits nuclear and mitochondrial DNA replication in S. cerevisiae at 15 mM and...
Keywords: ara-CMP
CAS 7075-11-8
MW: 323.198 D
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